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In *SURMOUNT-MAINTAIN*, Eli Lilly randomized patients who reached goal weight on their maximum tolerated tirzepatide dose into three arms: continue at max dose, step down to 5 mg, or switch to placebo

They looked at the results of 39 published studies, and determined there is significant evidence that two specific pathways for detoxification are impaired in autism, and that large trials are needed for children with autism to determine if boosting the function of these two pathways will likewise improve autistic behaviors

MC1R is a G-protein-coupled receptor expressed primarily on melanocytes

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What they did: Isolated human chondrocytes (from osteoarthritis patients and healthy donors) were exposed to AOD-9604 at doses 1 to 1000 nM

Supports brain and nerve function: Pyridoxine helps make neurotransmitters, while Nicotinamide supports cellular repair and energy production